GOAL Create an explainer series covering Bayer’s NUBEQA treatment for nonmetastatic castration-resistant prostate cancer (nmCRPC). The purpose of the series was to inform prescribers and caregivers on the accessibility, efficacy, and tolerability of the treatment. Challenge Our challenge was to create a campaign for Bayer’s treatment that would be narratively compelling and visually exciting, while working within the strict guidelines of pharmaceutical advertising regulation. Our Approach In order to stay within the regulatory guidelines the campaign was split into two parts; branded, and unbranded. Branded videos could utilize the NUBEQA brand guidelines provided by Bayer, while unbranded videos would use similar visual elements but remain distanced from the NUBEQA treatment. Branded videos would specifically reference the NUBEQA treatment, and would thereby require less specific claims, and for elements like Indication, Important Safety Information, and points of context to be added throughout the video. Unbranded videos would serve as educational content, speak more generally to caregivers about nmCRPC and be able to speak more specifically about treatment, but would avoid referencing the NUBEQA treatment.